Featured Malaria Publication - Transmission and Control of Plasmodium knowlesi

24 July 2014

Conventional control measures are sufficient to reduce the risk of P. knowlesi infection in humans if actively implemented

Transmission and Control of Plasmodium knowlesi: A Mathematical Modelling Study

Natsuko Imai, Michael T. White, Azra C. Ghani and Chris J. Drakeley

Plasmodium knowlesi is a malaria of macaques which is now recognised as a leading cause of human malaria in Malaysia. Although current human infections are a result of human-macaque contact, there is a potential for P. knowlesi to be transmitted solely among humans. The authors developed a multi-host, multi-site transmission model to assess the likelihood of this happening due to increased human-macaque contact as a consequence of deforestation, population growth, and land-use change. How effective currently available malaria control measures were against P. knowlesi was also an important issue that was explored using the model. Although the model predicts that conventional control measures will be sufficient against P. knowlesi, with the push to eliminate malaria by the end of 2015, it is crucial to be aware of zoonotic malarias which may undermine such efforts.

Read the full article in PLOS Neglected Tropical Diseases.