Featured Malaria Publication - Infection detection technologies for malaria elimination and eradication

31 May 2014

Malaria elimination goals require active infection detection. The epidemiology of low prevalence regions drives active infection tactics. New diagnostic tools can improve efficiencies for malaria elimination programmes. New diagnostics should be guided by thoughtful target product profile development.

The essential role of infection-detection technologies for malaria elimination and eradication

Kathleen Tietje,  Kenneth Hawkins,  Christine Clerk,  Kelly Ebels,  Sarah McGray,  Chris Crudder, Lucy Okell and Paul LaBarre

Recent emphasis on malaria elimination and eradication (E&E) goals is changing the way that experts evaluate malaria diagnostic tools and tactics. As prevalence declines, the focus of malaria management is pivoting toward low-density, sub-clinical infections and geographically and demographically concentrated reservoirs. These and other changes present challenges and opportunities for innovations in malaria diagnostics aimed at meeting the needs of malaria elimination programmes. Developing such technologies requires a review of the operational approaches to detecting malaria infections in areas of declining prevalence. The authors review recent research on epidemiology and biology related to malaria elimination and operational factors that influence E&E strategies. They further propose use-scenarios and a target product profile framework to define and prioritize the required attributes of infection-detection technologies.

Read the full article in Trends in Parasitology