The Diagnostics Modelling Consortium directs research under five core health themes:

  • Malaria

  • HIV

  • Neglected Tropical Diseases

  • Pneumonia and

  • Point of Care initiatives

Further details about each project can be found below.


Malaria, caused by the Plasmodium parasite, is a major cause of childhood mortality in low and middle-income countries, resulting in an estimated 660,000 deaths in 2012, with the majority occurring in children under the age of 5 in sub-Saharan Africa.


An estimated 34 million people are currently living with HIV worldwide, half of whom do not know their status.


Neglected tropical diseases are a medically diverse group of infections caused by a variety of pathogens including viruses, bacteria, protozoa and helminths. The 17 neglected tropical diseases prioritized by WHO are estimated to affect more than 1 billion people worldwide and are endemic in 149 countries.


While global child deaths have declined from an estimated 12.6 million to 6.6 million over the last two decades, pneumonia has remained a leading worldwide cause of death among children under age 5.

Point of Care

Diagnostics have traditionally been developed for single pathogens and using multiple different technological platforms. The BMGF approach to investment in diagnostics research is proposing to move away from single tests for a single outcome to an integrated platform with tests for multiple outcomes using multiple technologies.